Bioadhesive Analysis of Controlled-release Systems. Iv. an Experimental Method for Testing the Adhesion of Microparticles with Mucus
نویسندگان
چکیده
A new and simple method for testing and classifying the bioadhesive behavior of polymeric microparticles,with or without drugs is presented. The method is used to determine the adhesive forces between solid polymeric microparticles of diameter up to 200 pm in contact with natural rn~os~ or with a mucin gel. A t~oret~ul analysis is presented in order to calcu~te the ~~sive c~r~ter~tics of spherical m~rop~rtic~s in contact with rn~~.
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